A Finite Element Study of Micropipette Aspiration of Single Cells: Effect of Compressibility

<table>The FE results for NHVH cell model with different values of the Prony shear relaxation parameter <svg height="18.887501" id="M73" style="vertical-align:-3.56265pt" version="1.1" viewbox="0 0 17.475 18.887501" width="17.475" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>. Other parameters were Prony bulk relaxation parameter <svg height="16.725" id="M74" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 43.9375 16.725" width="43.9375" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, time constant <svg height="11.225" id="M75" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 47.950001 11.225" width="47.950001" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> (s), initial shear modulus <svg height="15.6875" id="M76" style="vertical-align:-3.39066pt" version="1.1" viewbox="0 0 62.662498 15.6875" width="62.662498" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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<g transform="matrix(.017,0,0,-.017,23.425,11.4)"><path d="M535 323h-483v50h483v-50zM535 138h-483v50h483v-50z" id="x3D"></path></g><g transform="matrix(.017,0,0,-.017,38.112,11.4)"><path d="M456 178h-96v-72q0 -51 12.5 -62.5t72.5 -16.5v-27h-256v27q65 5 78 17t13 62v72h-260v28q182 271 300 426h40v-407h96v-47zM280 225v295h-2q-107 -148 -196 -295h198z" id="x34"></path></g><g transform="matrix(.017,0,0,-.017,46.271,11.4)"><path d="M384 0h-275v27q67 5 81.5 18.5t14.5 68.5v385q0 38 -7.5 47.5t-40.5 10.5l-48 2v24q85 15 178 52v-521q0 -55 14.5 -68.5t82.5 -18.5v-27z" id="x31"></path></g><g transform="matrix(.017,0,0,-.017,54.431,11.4)"><path d="M456 178h-96v-72q0 -51 12.5 -62.5t72.5 -16.5v-27h-256v27q65 5 78 17t13 62v72h-260v28q182 271 300 426h40v-407h96v-47zM280 225v295h-2q-107 -148 -196 -295h198z" id="x34"></path></g>
</svg> (Pa), Poisson’s ratio <svg height="11.125" id="M77" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 56.0625 11.125" width="56.0625" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, and aspiration pressure of <svg height="11.425" id="M78" style="vertical-align:-0.20474pt" version="1.1" viewbox="0 0 54.837502 11.425" width="54.837502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> (Pa).</table>

Computational and Mathematical Methods in Medicine

fig5

Figure 5

Figure 5: A Finite Element Study of Micropipette Aspiration of Single Cells: Effect of Compressibility 