Table 4: Test dataset Goodness of fit comparisons. Clinical MRTD values from 8 ARVs were using as and external test dataset the validate model predictability. Model performance is characterized here in terms of root means squared error (RMSE), Kendall’s correlation coefficient (tau), and Type II error probability ( -value).

DrugMRTDMLRSETNNSE

Abacavir10.00−10.6738427.40606.486112.3474
Emtricitabine4.00−23.9239779.74413.36780.3996
Raltegravir30.070.0628900.432019.7700106.0900
Nevirapine3.00−54.18623270.2614−16.5700382.9849
Efavirenz10.10−10.2863415.6012−5.7782252.1172
Fosamprenavir46.7044.05157.014550.750016.4025
Atazanavir5.3511.436037.039329.8700601.2304
Lopiravir53.3342.6361114.359464.5900126.7876

Mean20.32−0.1105RMSE = 27.2719.06RMSE = 13.67
Kendall’s tau0.7140.643
-value0.0190.035