Research Article

Coarse-Grained Simulation of Myosin-V Movement

Figure 3

Myosin steps. Superposed frames of myosin molecules retaken from a simulation with (a) a stiff leg (good) and (b) a more flexible leg (weak). In both parts, a line connect the mid points of sequential domains which is drawn thicker in the bound myosin with one of the binding domains marked by a sphere. The colours represent active powerstroke (green), postpowerstroke conformation (red), unbound (blue), and loosely bound (cyan).
781456.fig.003a
(a) good
781456.fig.003b
(b) weak