Research Article

Coarse-Grained Simulation of Myosin-V Movement

Figure 6

Step Size Histograms for the Movement of MyoV. Plots are for myoV-2IQ (a), myoV-4IQ (b), and myoV-6IQ (c). -axis shows the number of events (F). axis shows the number of actin units separating the two myosin heads of the dimer when both are bound to the actin track. Separation by a single actin unit represents a distance of roughly 5.70 nm. Fit to a Gaussian distribution as follows: mean ± s.d., 2IQ = 3.0 ± 0.0, 4IQ = 4.64 ± 0.93, 6IQ = 6.07 ± 0.95.
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(a)
781456.fig.006b
(b)
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(c)