Membrane Protein Stability Analyses by Means of Protein Energy Profiles in Case of Nephrogenic Diabetes Insipidus

<table>Illustration of the water binding network in aquaporin-1 (PDB_ID 1fqy). Due to high residue conservation, knowledge gained from known aquaporin structures can be assigned to aquaporin-2 reliably. Since there is no high resolution structure of aquaporin-2, this gained knowledge sheds light on the structure-function relationship in aquaporin-2.</table>

Computational and Mathematical Methods in Medicine

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Figure 1

Figure 1: Membrane Protein Stability Analyses by Means of Protein Energy Profiles in Case of Nephrogenic Diabetes Insipidus 