Review Article

Analyzing Effects of Naturally Occurring Missense Mutations

Figure 1

(a) The structural and flexibility differences between the simulated WT and mutant structures. The black line represents the RMSF of the WT structure and the red line represents the mutant protein. (b) 3D structure of the C2 domain of the WT FV. The S–S bond is marked in yellow and the loop 2042–2053 is indicated by the arrow.
805827.fig.001a
(a)
805827.fig.001b
(b)