Review Article

Analyzing Effects of Naturally Occurring Missense Mutations

Figure 4

Effects on monomer stability. (a) G56S: N-terminal domain of both WT monomer (white) and mutant monomer (green) are superimposed. Cyan stick represented Gly in the WT structure and magenta represented Ser in the mutant structure; (b) V132G: C-terminal domain of both WT monomer (white) and mutant monomer (green) are superimposed. We use stick and ball representation in orange to represent Val in the WT structure and in red to represent Gly in the mutant structure.
805827.fig.004a
(a)
805827.fig.004b
(b)