The Number of Candidate Variants in Exome Sequencing for Mendelian Disease under No Genetic Heterogeneity
Figure 2
The expected number of SNVs after filtering in dominant disease using unrelated individuals (a) without controls (b) with controls. For example, cross marks represent the expected number of SNVs in which ≥80% individuals have the genotype of affected individuals and ≤20% individuals have the genotype of controls.
