393792.fig.005a
(a)
393792.fig.005b
(b)
393792.fig.005c
(c)
393792.fig.005d
(d)
393792.fig.005e
(e)
393792.fig.005f
(f)
Figure 5: Top: the left ventricular pressure-volume loop (a), the left ventricular pressure (- -) and aortic (-) pressure (b), and the flow through the aortic (-) and mitral (- -) valve (c), adapted from Van De Vosse and Stergiopulos [8] (Figure 3). The pressure-volume loop in (a) is determined from the data in (b) and (c) with the end-systolic volume assumed to be 45 mL. Bottom: similar signals obtained with the model.