Comparison of Simple Models of Periodic Protocols for Combined Anticancer Therapy

Table 5

Comparison of results from mathematical and biological protocols.

Protocol	Progression-free survival	Tumor volume after 21 days simulation
SU 37.5 mg; CIS 60 mg/m^2, CAP 1600 mg/m^2	3.2 months; (2.7 to 9.3)	5249.1 mm^3
SU 37.5 mg; CIS 60 mg/m^2, CAP 2000 mg/m^2	6.6 months; (2.5 to 8.0)	4071.5 mm^3
SU 25 mg; CIS 80 mg/m^2, CAP 2000 mg/m^2	6.4 months; (4.3 to 13.9)	4370.3 mm^3
SU 37.5 mg; OXA 110 mg/m^2, CAP 1600 mg/m^2	8.0 months; (4.7 to 9.4)	4963.9 mm^3
SU 37.5 mg; OXA 110 mg/m^2, CAP 2000 mg/m^2	2.8 months; (2.3 to 11.7)	3830.0 mm^3
SU 25 mg; OXA 110 mg/m^2, CAP 2000 mg/m^2	5.5 months; (4.7 to 10.1)	4623.9 mm^3