Power and Stability Properties of Resampling-Based Multiple Testing Procedures with Applications to Gene Oncology Studies

Table 1

Comparison of the estimated FWER and power for the resampling-based multiple testing procedures with FWER controlled at 5%.

	(𝑚−𝑚0)/𝑚	mt.maxT	mt.minP	ss.maxT	ss.minP	sd.maxT	sd.minP
FWER	0.10	0.00	0.00	0.18	0.53	0.14	0.53
	0.25	0.00	0.00	0.07	0.19	0.05	0.19
	0.50	0.00	0.00	0.02	0.06	0.02	0.07
	0.75	0.00	0.00	0.01	0.02	0.01	0.02
	0.90	0.00	0.00	0.00	0.01	0.00	0.01
Power	0.10	0.00	0.00	0.11	0.27	0.09	0.30
	0.25	0.00	0.00	0.12	0.32	0.11	0.32
	0.50	0.00	0.00	0.10	0.28	0.09	0.29
	0.75	0.00	0.00	0.11	0.27	0.10	0.28
	0.90	0.00	0.00	0.11	0.28	0.11	0.28

mt.maxT: permutation single-step maxT procedure; mt.minP: permutation single-step minP procedure; ss.maxT: bootstrap single-step maxT procedure; ss.minP: bootstrap single-step minP procedure; sd.maxT: bootstrap step-down maxT procedure; sd.minP: bootstrap step-down minP procedure.