Research Article

Application of Design of Experiment for Floating Drug Delivery of Tapentadol Hydrochloride

Table 5

Kinetic modeling of formulations (F1–F9).

Batch Best fitting model

F10.632125.9854Peppas
F20.658225.3902Peppas
F30.710222.5277Hixon-Crowel
F40.700823.6991Peppas
F50.623929.1835Peppas
F60.637425.6453Peppas
F70.592628.2604Peppas
F80.656327.2530Peppas
F90.564131.6038Matrix