Research Article
Application of Design of Experiment for Floating Drug Delivery of Tapentadol Hydrochloride
Table 5
Kinetic modeling of formulations (F1–F9).
| Batch | | | Best fitting model |
| F1 | 0.6321 | 25.9854 | Peppas | F2 | 0.6582 | 25.3902 | Peppas | F3 | 0.7102 | 22.5277 | Hixon-Crowel | F4 | 0.7008 | 23.6991 | Peppas | F5 | 0.6239 | 29.1835 | Peppas | F6 | 0.6374 | 25.6453 | Peppas | F7 | 0.5926 | 28.2604 | Peppas | F8 | 0.6563 | 27.2530 | Peppas | F9 | 0.5641 | 31.6038 | Matrix |
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