Optimisation of a Generic Ionic Model of Cardiac Myocyte Electrical Activity

Figure 2

Generic model fits to a range of APs recorded from many myocytes. Optimised models overlaid with five recorded intact tissue APs from each of rabbit central SAN (cSAN), peripheral SAN (pSAN), and right atrial (RA) myocytes. Each single dataset was separately fitted with two time-dependent membrane currents and one leakage current. The average and standard deviation of the root mean square (RMS) error of the fits is also shown.