Optimisation of a Generic Ionic Model of Cardiac Myocyte Electrical Activity

Table 4

Initial model variable values for LA multidataset-based optimisation.

	Run 1	Run 2	Run 3
Variable (PI = 400 ms)
𝐸𝑚(mV)	−80.32	−79.26	−79.86
𝑝1	0.99	0.95	0.70
𝑞1	0	0	0
𝑝2	0.07	2.70𝑒−2	2.20𝑒−2
𝑞2	0.45	0.46	0.11
𝑝3	6.00𝑒−4	0	3.00𝑒−4
𝑞3	0.87	0.84	0.92
𝑝4	2.70𝑒−3	4.40𝑒−3	2.2𝑒−3
𝑞4	0.11	8.90𝑒−2	0.126
𝑝5	4.00𝑒−3	0	2.00𝑒−4
𝑞5	0.16	0.31	0.264
Variable (PI = 200 ms)
𝐸𝑚(mV)	−77.80	−77.80	−78.61
𝑝1	0.99	0.99	0.72
𝑞1	0	0	0
𝑝2	0.90	0.90	2.70𝑒−2
𝑞2	0.42	0.42	0.133
𝑝3	1.80𝑒−3	1.80𝑒−3	4.00𝑒−4
𝑞3	0.64	0.64	0.883
𝑝4	6.90𝑒−3	6.90𝑒−3	2.70𝑒−3
𝑞4	5.70𝑒−2	5.70𝑒−2	0.102
𝑝5	8.10𝑒−3	8.10𝑒−3	1.50𝑒−3
𝑞5	3.50𝑒−2	3.50𝑒−2	0.26
Variable (PI = 300 ms)
𝐸𝑚(mV)	−80.40	−82.14	−79.96
𝑝1	0.99	0.52	0.69
𝑞1	0	0	0
𝑝2	6.60𝑒−2	4.50𝑒−2	2.20𝑒−2
𝑞2	0.45	0.45	0.109
𝑝3	6.00𝑒−3	5.00𝑒−4	3.00𝑒−4
𝑞3	0.87	0.93	0.922
𝑝4	2.60𝑒−3	2.90𝑒−3	2.20𝑒−3
𝑞4	0.113	0.14	0.128
𝑝5	2.00𝑒−4	6.00𝑒−4	1.00𝑒−4
𝑞5	0.16	0.27	0.264