Table 7: Parameter values for drug-specific optimisation.

ParameterDescription

Maximum conductance (µS/cm2)97127.612438.40 (Control)12279.6713.58
1562.28 (E-4031)
Reversal potential (mV)−55.54−97.79−79.9643.39−99.56
Maximum value of 4988.663178.2631282545.56
Slope value for −0.2
Maximum value of 2383.244828.3972.521965.64
Slope value for 0.19
value for and −89.6216.619.817.38
Maximum value of 587.8185.64162.530.83
Slope value for −0.1 0.2
Maximum value of 4049.79920.57185.4812.01
Slope value for 0.184−0.14
value for and −84.76−17.22−99.92−22.4