Research Article
Mathematical Modeling of the HIV/Kaposi’s Sarcoma Coinfection Dynamics in Areas of High HIV Prevalence
Table 1
Parameter values and their estimates.
| Parameter | Symbol | Value | Source |
| HIV rate of transmission | | 0.4801* | Baggaley et al. [5], | Boily et al. [6] | Death due to AIDS | | 0.333 | Malunguza et al. [7], | Mukandavire et al. [8] | Death due to AIDS with KS | | 0.067* | Malunguza et al. [7], | Mukandavire et al. [8] | Rate of KS acquisition among HIV-infected cohort | | 0.001 | Assumed | Rate of KS acquisition among pre-AIDS cohort | | 0.002 | Assumed | Rate of KS acquisition among AIDS cohort | | 0.003 | Assumed | Relative HIV infectiousness of an HIV-infected individual | | 0.8 | Assumed | Relative HIV infectiousness of a coinfected individual | | 1.1 | Assumed | Relative HIV infectiousness of a pre-AIDS individual | | 1.2 | Assumed | Relative HIV infectiousness of an AIDS individual | | 1.3 | Assumed | Recruitment rate of sexually mature individuals | | 800* | Barley et al. [9], | Malunguza et al. [7] | Mukandavire et al. [8, 10, 11] | Natural mortality rate | | 0.02 | Mukandavire et al. [8] | Treatment rate of infected and coinfected cohorts | | Varies | Assumed | Treatment rate of pre-AIDS and pre-AIDS coinfected cohorts | | Varies | Assumed | Natural progression to pre-AIDS | | 0.01 | Assumed | Rate of acute KS development in coinfected cohort | | 0.0001 | Assumed | Rate of acute KS development in pre-AIDS coinfected cohort | | 0.0002 | Assumed | Rate of acute KS development in AIDS coinfected cohort | | 0.0003 | Assumed | Natural progression to AIDS | | 0.1 | Mukandavire et al. [8, 10, 11] | Natural progression to AIDS after treatment | | 0.1 | Assumed |
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Denotes a parameter obtained by modifying a value in the given source.
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