Transcriptional Protein-Protein Cooperativity in POU/HMG/DNA Complexes Revealed by Normal Mode Analysis
Figure 1
(a) The 3D structure of the POU/HMG/DNA ternary complex 1GT0. The gray protein represents an HMG factor Sox-2, and the red one is a POU factor Oct-1, which is composed of two subunits POUS and POUHD. (b) The two reassembled protein pairs, originated from (a), for our subsequent studies.