Optimisation of Ionic Models to Fit Tissue Action Potentials: Application to 3D Atrial Modelling
Figure 7
Optimised LA and PV ionic models using a combined LA-PV 2D axisymmetric disc model. (a) The optimised LA and PV AP waveforms () are overlaid on top of AP traces recorded experimentally () from LA and PV tissue-intact myocytes from respective rabbit tissue preparations. (b) Inward, outward, and leakage ionic currents reconstructed from the optimised LA and PV nodes in the combined disc model.