Application of Genetic Algorithm for Discovery of Core Effective Formulae in TCM Clinical Data

Table 2

Top 50 frequently used herbs.

Rank	Record based		Patient based
	Herb	Frequency	Herb	Frequency
1	Chinese sage herb	395	Chinese sage herb	147
2	Doederlein's spikemoss herb	393	Doederlein's spikemoss herb	146
3	Akebia fruit	359	Akebia fruit	133
4	Herba oldenlandiae	332	Herba oldenlandiae	129
5	Atractylis ovata	321	Atractylis ovata	127
6	Rice-grain sprout	268	Astragalus root	116
7	Malt	268	Pachyma cocos	107
8	Pachyma cocos	266	Chicken gizzard membrane	107
9	Astragalus root	263	Rice-grain sprout	106
10	Chicken's gizzard-membrane	252	Malt	106
11	Common selfheal spike	239	Common selfheal spike	104
12	Rhizoma batatatis	235	Rhizoma batatatis	97
13	Coix seed	223	Coix seed	96
14	Tangerine peel	195	Coastal glehnia root	86
15	Coastal glehnia root	195	Oysters	85
16	Oysters	183	Tangerine peel	80
17	Rhizoma amorphophalli	172	Pericarpium trichosanthis	79
18	Pericarpium trichosanthis	162	Asparagus cochinchinensis	72
19	Asparagus cochinchinensis	158	Rhizoma amorphophalli	68
20	Edible tulip	139	Edible tulip	64
21	Crataegus pinnatifida	133	Crataegus pinnatifida	62
22	Ophiopogon japonicus	122	Tatarian aster root and rhizome	58
23	Chinese date	120	Shorthorned epimedium herb	58
24	Glycyrrhiza uralensis	119	Pilose asiabell root	58
25	Pilose asiabell root	119	Ophiopogon Japonicus	57
26	Tatarian aster root and rhizome	112	Glycyrrhiza uralensis	55
27	Chinese taxillus herb	111	Chinese taxillus herb	53
28	Shorthorned epimedium herb	109	Chinese date	53
29	Pinellia tuber	99	Pinellia tuber	51
30	Baikal skullcap root	98	Heartleaf houttuynia herb	48
31	Suberect spatholobus stem	97	Suberect spatholobus stem	46
32	Heartleaf houttuynia herb	95	Glossy privet fruit	46
33	Glossy privet fruit	91	Baikal skullcap root	45
34	Noble dendrobium stem herb	89	Balloon flower root	43
35	Chekiang fritillary bulb	82	Chekiang fritillary bulb	42
36	Paris polyphylla smith	79	Eucommia bark	40
37	Almond	78	Paris polyphylla smith	40
38	Eucommia bark	76	Barbary wolfberry fruit	40
39	Balloon flower root	75	Almond	40
40	Barbary wolfberry fruit	73	Noble Dendrobium stem herb	39
41	Pyrrosia leaf	65	Cherokee rose fruit	35
42	Cherokee rose fruit	63	Chinese dodder seed	32
43	Reed rhizome	57	Pyrrosia leaf	31
44	Toad skin	57	Reed rhizome	30
45	Radix semiaquilegia	55	Toad skin	30
46	Fingered citron fruit	55	Common macrocarpa fruit	29
47	Chinese dodder seed	54	Immature bitter orange	28
48	Common macrocarpa fruit	53	Radix Semiaquilegia	25
49	Dragon's bones	51	Radish seed	24
50	Immature bitter orange	51	Dragon's bones	24