DV-Curve Representation of Protein Sequences and Its Application

<table>The representation of four alphabets of DV-curve: (a) <svg height="15.25" id="M17" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 16.950001 15.25" width="16.950001" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.112)"><path d="M594 511q0 -122 -171 -157l1 -2q158 -33 158 -159q0 -52 -34.5 -95t-90.5 -65q-76 -33 -217 -33h-223l8 28q63 5 79.5 19t26.5 72l83 426q9 48 -2.5 60t-77.5 17l6 28h259q195 0 195 -139zM499 509q0 59 -37 83t-91 24q-36 0 -51 -9q-17 -9 -22 -44l-35 -195h62
q82 0 128 37t46 104zM481 199q0 71 -48 102.5t-121 31.5h-56l-37 -201q-11 -58 7.5 -77t80.5 -19q76 0 125 44.5t49 118.5z" id="x1D435"></path></g>
<g transform="matrix(.012,-0,0,-.012,10.55,15.187)"><path d="M384 0h-275v27q67 5 81.5 18.5t14.5 68.5v385q0 38 -7.5 47.5t-40.5 10.5l-48 2v24q85 15 178 52v-521q0 -55 14.5 -68.5t82.5 -18.5v-27z" id="x31"></path></g>
</svg>, (b) <svg height="15.25" id="M18" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 16.950001 15.25" width="16.950001" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.112)"><path d="M594 511q0 -122 -171 -157l1 -2q158 -33 158 -159q0 -52 -34.5 -95t-90.5 -65q-76 -33 -217 -33h-223l8 28q63 5 79.5 19t26.5 72l83 426q9 48 -2.5 60t-77.5 17l6 28h259q195 0 195 -139zM499 509q0 59 -37 83t-91 24q-36 0 -51 -9q-17 -9 -22 -44l-35 -195h62
q82 0 128 37t46 104zM481 199q0 71 -48 102.5t-121 31.5h-56l-37 -201q-11 -58 7.5 -77t80.5 -19q76 0 125 44.5t49 118.5z" id="x1D435"></path></g>
<g transform="matrix(.012,-0,0,-.012,10.55,15.187)"><path d="M412 140l28 -9q0 -2 -35 -131h-373v23q112 112 161 170q59 70 92 127t33 115q0 63 -31 98t-86 35q-75 0 -137 -93l-22 20l57 81q55 59 135 59q69 0 118.5 -46.5t49.5 -122.5q0 -62 -29.5 -114t-102.5 -130l-141 -149h186q42 0 58.5 10.5t38.5 56.5z" id="x32"></path></g>
</svg>, (c) <svg height="15.4" id="M19" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 16.950001 15.4" width="16.950001" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.112)"><path d="M594 511q0 -122 -171 -157l1 -2q158 -33 158 -159q0 -52 -34.5 -95t-90.5 -65q-76 -33 -217 -33h-223l8 28q63 5 79.5 19t26.5 72l83 426q9 48 -2.5 60t-77.5 17l6 28h259q195 0 195 -139zM499 509q0 59 -37 83t-91 24q-36 0 -51 -9q-17 -9 -22 -44l-35 -195h62
q82 0 128 37t46 104zM481 199q0 71 -48 102.5t-121 31.5h-56l-37 -201q-11 -58 7.5 -77t80.5 -19q76 0 125 44.5t49 118.5z" id="x1D435"></path></g>
<g transform="matrix(.012,-0,0,-.012,10.55,15.187)"><path d="M285 378v-2q65 -13 102 -54.5t37 -97.5q0 -57 -30.5 -104.5t-74 -75t-85.5 -42t-72 -14.5q-31 0 -59.5 11t-40.5 23q-19 18 -16 36q1 16 23 33q13 10 24 0q58 -51 124 -51q55 0 88 40t33 112q0 64 -39 96.5t-88 32.5q-29 0 -64 -11l-6 29q77 25 118 57.5t41 84.5
q0 45 -26.5 69.5t-68.5 24.5q-67 0 -120 -79l-20 20l43 63q51 56 127 56h1q66 0 107 -37t41 -95q0 -42 -31 -71q-22 -23 -68 -54z" id="x33"></path></g>
</svg>, and (d) <svg height="15.25" id="M20" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 16.950001 15.25" width="16.950001" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.112)"><path d="M594 511q0 -122 -171 -157l1 -2q158 -33 158 -159q0 -52 -34.5 -95t-90.5 -65q-76 -33 -217 -33h-223l8 28q63 5 79.5 19t26.5 72l83 426q9 48 -2.5 60t-77.5 17l6 28h259q195 0 195 -139zM499 509q0 59 -37 83t-91 24q-36 0 -51 -9q-17 -9 -22 -44l-35 -195h62
q82 0 128 37t46 104zM481 199q0 71 -48 102.5t-121 31.5h-56l-37 -201q-11 -58 7.5 -77t80.5 -19q76 0 125 44.5t49 118.5z" id="x1D435"></path></g>
<g transform="matrix(.012,-0,0,-.012,10.55,15.187)"><path d="M456 178h-96v-72q0 -51 12.5 -62.5t72.5 -16.5v-27h-256v27q65 5 78 17t13 62v72h-260v28q182 271 300 426h40v-407h96v-47zM280 225v295h-2q-107 -148 -196 -295h198z" id="x34"></path></g>
</svg>.</table>

Computational and Mathematical Methods in Medicine

DV-Curve Representation of Protein Sequences and Its Application

Figure 1