Mathematical Modeling of Transmission Dynamics and Optimal Control of Vaccination and Treatment for Hepatitis B Virus

<table>The plot shows the sensitivity of carrier populations for different values of control <svg height="11.825" id="M260" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 15.6 11.825" width="15.6" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,7.675)"><path d="M515 96q-37 -44 -84.5 -76t-71.5 -32q-12 0 -18 7t-6 34t10 75l19 89h-2q-87 -113 -181 -176q-43 -29 -83 -29q-46 0 -46 63q0 31 9 67l52 222q7 36 -1 36q-10 0 -76 -50l-13 24q47 45 92 71.5t67 26.5q18 0 21 -16.5t-8 -65.5l-56 -242q-16 -67 13 -67q41 0 114 74
t114 146l32 145l74 26h11q-52 -199 -80 -347q-8 -39 6 -39q7 0 32 17.5t47 39.5z" id="x1D462"></path></g>
<g transform="matrix(.012,-0,0,-.012,9.213,11.762)"><path d="M412 140l28 -9q0 -2 -35 -131h-373v23q112 112 161 170q59 70 92 127t33 115q0 63 -31 98t-86 35q-75 0 -137 -93l-22 20l57 81q55 59 135 59q69 0 118.5 -46.5t49.5 -122.5q0 -62 -29.5 -114t-102.5 -130l-141 -149h186q42 0 58.5 10.5t38.5 56.5z" id="x32"></path></g>
</svg>.</table>

Computational and Mathematical Methods in Medicine

fig14

Figure 14

Figure 14: Mathematical Modeling of Transmission Dynamics and Optimal Control of Vaccination and Treatment for Hepatitis B Virus 