Application of Multivariate Modeling for Radiation Injury Assessment: A Proof of Concept

Figure 2

Candidate NHP blood parameters considered in the formulation of the CBC and CBC-SCHEM RC3 models (a) ANC, (b) ALC, (c) APC in (×10³ cells μL⁻¹), (d) abundance HCT in %, (e) CK, (f) AST, and (g) LDH in UL⁻¹. The seven blood parameters were graphed with their standard errors for detecting the radiosensitivity of NHPs to a 6.5 Gy ⁶⁰Co γ-radiation dose on d 0 (nonirradiated, ) and 7, 10, 14, 17, 21, and 25 d after irradiation () (shaded areas indicate range between upper and lower 95% confidence levels).

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