A Mixture Modeling Framework for Differential Analysis of High-Throughput Data
Figure 2
Results from fitting DIME to the ChIP-seq data, where designates a differential component. (a) The histogram of the methylation data is superimposed by the fitted best model and the individual components (inset: zoomed in view showing the individual components of the fitted model). (b) The QQ-plot of the best model versus the observed normalized ChIP-seq data.
