A Mixture Modeling Framework for Differential Analysis of High-Throughput Data
Figure 3
Results from fitting the weighted DIME to the DNA methylation data, where * designates a differential component. ((a)–(c)) The histogram of the methylation data is superimposed by the fitted best model showing the fit of the model. Individual components of the best model are also shown to be superimposed on the histogram. (d) The Venn diagram showing the number of uniquely methylated loci in each of the three cell lines and the number of methylated loci shared between the three different cell lines.
