A Mixture Modeling Framework for Differential Analysis of High-Throughput Data

Table 1

Summary of three types of real datasets.

Data type	Description	Positive control	Negative control
ChIP-seq	Pol II comparison in MCF7 versus OHT	No	No
DNA methylation	MCF7 versus pooled normal	No	No
	T47D versus pooled normal	No	No
	MDA-MB-361 versus pooled normal	No	No
Gene expression	Apo AI knocked out versus normal mice	Yes	No
	HIV infected CD4^+ T cell versus noninfected	Yes	Yes