Correlating Information Contents of Gene Ontology Terms to Infer Semantic Similarity of Gene Products

Table 1

Fold changes of semantic similarity scores within protein families against those outside families.

𝑚	𝑛	Semantic similarity measures
		Correlation	Cosine	Jaccard	Wang	Resnik	Schlicker	Lin	Jiang
2	1022	6.915	6.511	3.267	1.856	2.370	2.669	2.331	1.524
3	562	8.986	8.446	3.827	1.988	2.680	3.100	2.641	1.629
4	360	9.608	8.760	4.027	2.037	2.799	3.247	2.761	1.656
5	240	9.359	9.135	4.131	2.065	2.843	3.324	2.827	1.662
6	182	9.997	9.214	4.224	2.105	2.901	3.410	2.888	1.692
7	141	10.10	9.741	4.363	2.106	2.952	3.476	2.918	1.690
8	110	9.921	9.409	4.432	2.101	2.853	3.409	2.895	1.661
9	89	9.880	9.321	4.445	2.094	2.857	3.419	2.908	1.643
10	75	9.814	9.273	4.516	2.090	2.846	3.430	2.898	1.644

m: minimum number of proteins in a family. n: number of protein families, each containing at least m proteins.