Enhancing the Detection of BOLD Signal in fMRI by Reducing the Partial Volume Effect

Figure 5

The measurement of peak 𝑡-score in each of the activations in the simulated data is shown in this plot. For each of the 24 activated regions, the 𝑦-axis represents the maximum 𝑡-score in the interpolated 128 × 128 map. The 𝑥-axis represents the maximum 𝑡-score in each of the four 64 × 64 maps. The highest of the four 𝑡-scores in each region is the same as the maximum 𝑡-score in that region in the interpolated map. This plot shows that the VSI can increase the 𝑡-score by up to 50% in single-voxel activations with a signal change of 1% (solid diamonds). The increase of 𝑡-score with VSI is substantial for single-voxel activations with a signal of up to 5% and 9-voxel activations with a signal change of 1%.