Increasing the Time Interval between PCV Chemotherapy Cycles as a Strategy to Improve Duration of Response in Low-Grade Gliomas: Results from a Model-Based Clinical Trial Simulation

Table 1

Expected percentages of patients still in response after treatment onset for the different protocols tested.

	PCV alone			RT + PCV
Years after treatment onset	Standard protocol	3-month protocol	6-month protocol	Standard protocol	RT + 3-month PCV protocol	RT + 6-month PCV protocol
2 years	72.6%	81.8%	96%	90.5%	92.1%	93.9%
3 years	53.6%	61.5%	82.2%	72.1%	73.7%	88.6%
4 years	37.1%	40.5%	59.5%	54.7%	56.3%	68.4%