In Silico Design of Human IMPDH Inhibitors Using Pharmacophore Mapping and Molecular Docking Approaches

Figure 5

Binding mode and 2D interaction map of hit compounds. (a) The binding mode of ZINC02090792 in the active site of IMPDH. (b) The 2D interaction map of ZINC02090792 with the active site of IMPDH. (c) The binding mode of ZINC00048033 in the active site of IMPDH. (d) The 2D interaction map of ZINC00048033 with the active site of IMPDH.

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