Identifying Novel Candidate Genes Related to Apoptosis from a Protein-Protein Interaction Network

Table 1

26 significant candidate genes, their betweenness, and permutation FDRs.

Row number	Ensembl ID	Gene name	Betweenness	Permutation FDR
1	ENSP00000316840	TRAF6	509	<0.002
2	ENSP00000365435	TNFRSF1B	86	<0.002
3	ENSP00000268182	IQGAP1	289	<0.002
4	ENSP00000268171	FURIN	252	<0.002
5	ENSP00000327850	NFATC1	95	<0.002
6	ENSP00000379330	NFATC2	238	<0.002
7	ENSP00000315615	AKAP5	195	<0.002
8	ENSP00000267169	DIABLO	138	<0.002
9	ENSP00000216160	TAB1	120	<0.002
10	ENSP00000246533	CAPNS1	86	<0.002
11	ENSP00000380349	CAPN3	86	<0.002
12	ENSP00000286355	ADCY8	167	0.002
13	ENSP00000382834	NPRL3	83	0.008
14	ENSP00000288840	SMAD6	25	0.014
15	ENSP00000304895	IRS1	238	0.016
16	ENSP00000237596	PKD2	3	0.016
17	ENSP00000296871	CSF2	65	0.02
18	ENSP00000404503	BBC3	8	0.02
19	ENSP00000277541	NOTCH1	249	0.022
20	ENSP00000360683	PTPN1	93	0.024
21	ENSP00000327048	MAF	54	0.026
22	ENSP00000189444	NFKB2	8	0.034
23	ENSP00000349467	CALM1	244	0.038
24	ENSP00000258682	CAMK2B	179	0.04
25	ENSP00000264122	CBLB	5	0.042
26	ENSP00000360266	JUN	211	0.044