From Heuristic to Mathematical Modeling of Drugs Dissolution Profiles: Application of Artificial Neural Networks and Genetic Programming

Table 3

Generalization errors (RMSE) obtained in the 5-fold cross-validation procedure for three equations fitted to the various datasets.

Dataset	Equation (7)	Equation (9)	Equation (10)
Original	2.32	21.02	10.58
Balanced	2.45	37.98	5.32
Noised	2.29	24.17	5.36
ANN-enhanced	2.33	2.19	2.13