Computational Insight into Protein Tyrosine Phosphatase 1B Inhibition: A Case Study of the Combined Ligand- and Structure-Based Approach

Figure 4

2D mapping of the pharmacophore features onto compounds representative of each family. The features were color-coded as follows: hydrophobic group (H) in cyan, aromatic ring (R) in orange, and hydrogen bond acceptor (A) in green. An attached × indicates that a feature was not mapped.