Research Article
Computational Insight into Protein Tyrosine Phosphatase 1B Inhibition: A Case Study of the Combined Ligand- and Structure-Based Approach
Table 1
Activities of the selected compounds.
| Compound | IC50 (nM) | (nM) | Ref. |
| 1 | 210 | | [16] | 2 | 185 | | [16] | 3 | 65 | | [16] | 4 | 110 | | [21] | 5 | 330 | | [21] | 6 | 31 | | [21] | 7 | 7 | | [17] | 8 | 90 | | [17] | 9 | | 36 | [18] | 10 | | 4 | [18] | 11 | | 13 | [22] | 12 | | 740 | [22] | 13 | | 310 | [18] | 14 | | 21 | [22] | 15 | | 22 | [22] | 16 | | 0.68 | [18] |
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