Topological Measurements of DWI Tractography for Alzheimer’s Disease Detection

Figure 1

The figure shows the processing pipeline underwent by brain DWI scans. The dotted box includes the dedicated image processing steps: (a) eddy correction, (b) brain extraction, and (c) affine registration. For each voxel the diffusion tensor was estimated, (d) thus allowing the probabilistic fiber reconstruction. Using the Harvard-Oxford atlas, the connectivity matrix derived from tractography was computed for each subject.