NSiteMatch: Prediction of Binding Sites of Nucleotides by Identifying the Structure Similarity of Local Surface Patches

Figure 5

The relation between the predictive quality of the NSiteMatch and Findsite and the similarity between the predicted protein and template library. The success rates (y-axis) are measured using (the minimal distance from the center of the predicted site to the center of the ligand) on the benchmark datasets. A given binding site is regarded as correctly predicted if the minimal distance between this site and the top predictions is below the cutoff distance D (x-axis), where is the number of binding sites of the protein that includes the evaluated binding site. (a), (c), and (e) evaluate results of the NSiteMatch for the ADP, ATP, and AMP, respectively; (b), (d), and (f) summarize the corresponding results for the Findsite.

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