The circulatory and reproductive systems can be considered as tubular transport systems of blood cells and gametes, respectively. They involve unsteady flows at both low and high Reynolds numbers, large displacements, and large deformations in the three-dimensional space and turbulent flow. In addition, multiple lengths and time scales and multiple processes need to be considered. Due to their importance in health and fundamentals, great effort has been put in developing numerical methods for these systems and in understanding the flow physics. In spite of the many achievements, it is still a challenge to model these systems accurately using numerical methods. Moreover, there still remains much concerted development towards grasping the complicated flow physics within such systems by using advanced numerical methods and mathematical models.

In this special issue, we invite investigators to contribute original research as well as review articles focusing on the development of numerical methods for complex flows and fluid-structure interaction in circulatory and reproductive systems or on addressing the complicated flow physics and heat and mass transfer in these systems for fundamental understanding as well as engineering applications. We are particularly interested in articles that advance numerical methods and their applications in such systems.

Potential topics include, but are not limited to:

• Numerical methods for circulatory and reproductive systems
• Circulatory and reproductive biofluid mechanics
• Fluid-structure interactions in circulatory and reproductive systems
• Numerical simulations with patient-specific geometries
• Flow dynamics and flow quantification in healthy, diseased, and surgically altered systems
• Sperm/cell dynamics and chemotaxis
• Arteriovenous-graft-thrombosis prediction
• Heat and mass transfer in circulatory and reproductive systems