Exploring the Limitations of Peripheral Blood Transcriptional Biomarkers in Predicting Influenza Vaccine Responsiveness

<div><i>Rationale for the computation of the titer response score.</i> The score integrates the responses obtained with the three strains represented in the TIV (H1N1, H3N2, and influenza B) by summing the logarithmic deviations of the <svg height="14.2543pt" id="M11" style="vertical-align:-5.4879pt" version="1.1" viewbox="-0.0498162 -8.7664 77.5041 14.2543" width="77.5041pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M729 650H468V622C546 615 554 610 554 527V365H213V527C213 610 221 616 297 622V650H38V622C120 616 128 611 128 527V123C128 39 120 34 40 28V0H303V28C221 34 213 40 213 123V322H554V123C554 39 546 34 460 28V0H728V28C647 34 639 39 639 123V527C639 610 647 615 729 622V650Z" id="g121-70"></path></g><g transform="matrix(.013,0,0,-0.013,9.475,0)"><path d="M673 0V28C608 34 594 43 563 129C499 303 432 494 370 665L339 656L132 132C98 43 84 37 20 28V0H238V28C162 35 154 45 175 108C188 150 203 192 219 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The circles of different radius on the top of the figure represent how the TRS was encoded as node size in Figure <a href="../fig6/">6</a>.</div>

Complexity

fig5

Figure 5

Figure 5: Exploring the Limitations of Peripheral Blood Transcriptional Biomarkers in Predicting Influenza Vaccine Responsiveness 