Research Article
Robust Nonnegative Matrix Factorization via Joint Graph Laplacian and Discriminative Information for Identifying Differentially Expressed Genes
Table 2
Pancreatic cancer genes extracted by GLD-RNMF.
| Gene ID | Gene name | Gene annotations | Relative diseases |
| 4313 | MMP2 | Serine-type endopeptidase activity and metallopeptidase activity | Arthropathy and multicentric osteolysis of Torg | 3486 | IGFBP3 | Fibronectin binding and insulin-like growth factor I binding. | Insulin-like growth factor I and acromegaly | 3630 | INS | Identical protein binding and protease binding | Diabetes mellitus | 4316 | MMP7 | Peptidase activity and metallopeptidase activity | Spastic entropion and focal myositis | 3880 | KRT19 | Structural molecule activity and structural constituent of cytoskeleton | Thyroid cancer and lung cancer | 7057 | THBS1 | Calcium ion binding and heparin binding | Posterior uveal melanoma and thrombotic thrombocytopenic purpura | 3320 | HSP90AA1 | Poly(A) RNA binding and identical protein binding | Lobular neoplasia and candidiasis | 1508 | CTSB | Peptidase activity and cysteine-type peptidase activity | Occlusion of gallbladder and ileum cancer | 7076 | TIMP1 | Cytokine activity and protease binding. | Oral submucous fibrosis and lung giant cell carcinoma | 2335 | FN1 | Heparin binding and protease binding | Glomerulopathy and plasma fibronectin deficiency |
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