Forebrain Ischemia Triggers GABAergic System Degeneration in Substantia Nigra at Chronic Stages in Rats

<table>The number of normal (i.e., vital) neurons in the striatum decreases rapidly after global ischemia. Bar graph shows normal neurons (mean ± SD) significantly decreased in rat striatum at days 3–56 after 12.5 minutes of transient forebrain ischemia, per high-power (40 <svg height="8.5" id="M78" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 10.1 8.5" width="10.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) microscopic field (*indicates the significant difference, ischemic versus sham groups, <svg height="15.2875" id="M79" style="vertical-align:-3.50804pt" version="1.1" viewbox="0 0 49.825001 15.2875" width="49.825001" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, ANOVA, post hoc Tukey HSD).</table>

Cardiovascular Psychiatry and Neurology

fig1

Figure 1

Figure 1: Forebrain Ischemia Triggers GABAergic System Degeneration in Substantia Nigra at Chronic Stages in Rats 