Targeting S100B in Cerebral Ischemia and in Alzheimer's Disease
Figure 3
Numerous -amyloid plaque-associated reactive astrocytes (positive for glial fibrillary acidic protein) are shown in a coronal brain section from a Tg2576 Alzheimer’s disease model mouse at 19 months of age. Higher magnification image (b) represents the inset of the lower magnification coronal brain section (a). Arrows show -amyloid plaques that are surrounded by glial fibrillary acidic protein-positive processes in the plaque periphery. Bars denote 500 m (a) and 50 m (b).