Review Article

Targeting S100B in Cerebral Ischemia and in Alzheimer's Disease

Figure 3

Numerous -amyloid plaque-associated reactive astrocytes (positive for glial fibrillary acidic protein) are shown in a coronal brain section from a Tg2576 Alzheimer’s disease model mouse at 19 months of age. Higher magnification image (b) represents the inset of the lower magnification coronal brain section (a). Arrows show -amyloid plaques that are surrounded by glial fibrillary acidic protein-positive processes in the plaque periphery. Bars denote 500  m (a) and 50  m (b).
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(a)
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(b)