Research Article

Effects of Neonatal Systemic Inflammation on Blood-Brain Barrier Permeability and Behaviour in Juvenile and Adult Rats

Table 1

Brain/plasma sucrose concentration ratios.

AgeControlLPS

P9 1 2 . 5 ± 0 . 6 ( 𝑛 = 6 ) 1 1 . 9 ± 1 . 6 ( 𝑛 = 6 )
P20 2 . 6 ± 0 . 2 ( 𝑛 = 6 ) 2 . 1 ± 0 . 1 ( 𝑛 = 6 )
Adult 2 . 3 ± 0 . 4 ( 𝑛 = 7 ) 4 . 2 ± 0 . 5 * ( 𝑛 = 7 )

Note: P9 ratios were from nephrectomised awake animals 3 hours after an i.p. injection, whereas ratios in older animals were 30 min ratios in anaesthetised animals after an i.v. injection. Data are mean ± SEM, * 𝑃 < . 0 5 from control, data published previously [11].