Blood-Brain Barrier Breakdown Following Traumatic Brain Injury: A Possible Role in Posttraumatic Epilepsy
Figure 1
Imaging modalities allow for BBB permeability evaluation and quantification. (a) Control subject: no BBB disruption is observed within the brain parenchyma (areas of significant differences are found in blood vessels, sinuses and the choroid plexus). Increased BBB permeability () and extravascular volume () are also localized to those same structures. (b) A 28-year-old PTE patient 10 days following TBI. A region of increased BBB permeability is detected over the left parietal lobe in both methods (arrows).