Table 5: Accuracy parameters of different cutoffs of ultrasound parameters for prediction of high white matter hyperintensities score (>20).

Ultrasound parameterCutoffSens.Spec.PPVNPVOverall
accuracy
Cohen’s AUC (95% CI)

CCA-Dmean (cm)0.80
(0.67–0.92)
<0.001
≥0.57696%46%64%92%71%0.423
≥0.66665%89%85%72%77%0.538
≥0.70539%96%91%61%67%0.346

CCA-PSV (cm/sec)0.69
(0.54–0.83)
0.022
≤34.66339%92%83%60%65%0.308
≤38.47062%69%67%65%65%0.308
≤45.31585%39%58%74%62%0.231

ICA-MFV (cm/sec)0.74
(0.60–0.88)
0.003
≤19.41527%100%100%58%64%0.269
≤27.54577%77%77%77%77%0.538
≤35.99092%31%57%80%62%0.231

MCA-PI0.82
(0.68–0.95)
<0.001
≥1.063100%68%74%100%83%0.671
≥1.18360%86%80%70%74%0.469
≥1.44525%91%71%57%60%0.164

Sens.: sensitivity, spec.: specificity, PPV: positive predictive value, NPV: negative predictive value, AUC: area under the receiver operating characteristic curve, CI: confidence interval.