Table 7: Causes of death categorised according to ICD-10 chapter in current users of typical and atypical antipsychotics.

ClassAtypicalTypical
Events ( , %)Incidence rate per 1000 person-years (95% CI)Events ( , %)Incidence rate per 1000 person-years (95% CI)

A00-B99: certain infectious and parasitic diseases63 [0.9]1.98 (1.52–2.53)46 [0.5]1.41 (1.03–1.89)
C00-D89: neoplasms/diseases of the blood and blood forming organs and certain disorders involving the immune mechanism585 [8.2]1.68 (1.55–1.83)3955 [43.1]4.83 (4.68–4.98)
E00-E90: endocrine, nutritional, and metabolic disorders114 [1.6]1.50 (1.24–1.80)106 [1.2]1.75 (1.43–2.12)
F00-F99: mental and behavioural disorders907 [12.7]1.45 (1.36–1.55)607 [6.6] 1.49 (1.37–1.61)
G00-G99: diseases of the nervous system657 [9.2]1.37 (1.27–1.48)384 [4.2]1.41 (1.27–1.55)
I00-I99: diseases of the circulatory system2119 [29.6]1.66 (1.59–1.73)1755 [19.1]1.72 (1.64–1.81)
I20-I25: ischemic heart disease670 [9.4]1.59 (1.48–1.72)570 [6.2]1.57 (1.44–1.70)
I50: heart failure108 [1.5]1.71 (1.40–2.07)94 [1.0]2.11 (1.70–2.58)
J00-J99: diseases of the respiratory system924 [12.9]1.52 (1.42–1.62)819 [8.9]1.57 (1.46–1.68)
K00-K93: diseases of the digestive system212 [3.0]1.33 (1.15–1.52)191 [2.1]1.40 (1.21–1.61)
L00-L99: diseases of the skin and subcutaneous tissue20 [0.3]2.78 (1.70–4.30)18 [0.2]1.22 (0.72–1.93)
M00-M99: diseases of the musculoskeletal system and connective tissue44 [0.6]1.83 (1.33–2.45)34 [0.4]1.90 (1.32–2.66)
N00-N99: disease of the genitourinary system183 [2.6]1.51 (1.30–1.74)162 [1.8]1.67 (1.42–1.94)
Q00-Q99: congenital malformations, deformations, and chromosomal abnormalities8 [0.1]2.04 (0.88–4.02)8 [0.1]2.13 (0.92–4.19)
R00-R99: symptoms, signs, and abnormal clinical and laboratory findings264 [3.7]1.58 (1.40–1.79)265 [2.9]2.08 (1.83–2.34)
V01-Y98: external causes of morbidity and mortality277 [3.9]1.63 (1.44–1.83)160 [1.7]1.26 (1.07–1.47)