Review Article

Cognitive Outcomes following Transcatheter Aortic Valve Implantation: A Systematic Review

Table 3

Summary of studies utilizing DW-MRI to view cerebral ischemia and assessed global cognition using the MMSE.

StudyType of TAVITime after TAVI that DW-MRI was performedNumber of patients with lesionsIncidence of patients with lesionsTotal number of lesionsAverage number of lesions per patient

Ghanem et al., 2013 [6]111TF (MCV) = 95
TF (ES) = 16
3 days36a64%

Knipp et al., 2013 [10]27TA (ES) = 2710.7 ± 4.9 days1258%221.83

Rodés-Cabau et al., 2011 [11]60TF (ES) = 29
TA (ES) = 31
4 ± 1 days19
22
66%
71%
83
168
4.37
7.63

Kahlert et al., 2010 [12]32TF (MCV) = 10
TF (ES) = 22
3.4 days (2.5–4.4)8
19
80%
86%
26
89
3.25
4.68

= number, TAVI = transcatheter aortic valve implantation, MMSE = mini-mental status examination, DW-MRI = diffusion weighted magnetic resonance imaging, ES = Edwards-SAPIEN, and MCV = Medtronic CoreValve.
aOnly 56 patients were able to undergo postprocedural imaging.