Research Article
Development and Validation of RP-HPLC Method for Quantitative Estimation of Vinpocetine in Pure and Pharmaceutical Dosage Forms
Table 3
Accuracy studies of vinpocetine in standard and drug-matrix solutions.
| | Amount added (μgmL−1) | Peak area | Amount recovered (μgmL−1) | % Recovery | Recovery (Mean ± %RSD) |
| Standard solution | 160 | 2758830 | 160.12 | 100.08 | | 160 | 2757741 | 160.06 | 100.04 | 100.05 ± 0.023 | 160 | 2757692 | 160.05 | 100.04 | | 180 | 3108421 | 180.41 | 100.23 | | 180 | 3108988 | 180.44 | 100.25 | 100.24 ± 0.012 | 180 | 3109134 | 180.45 | 100.25 | | 200 | 3463527 | 201.02 | 100.51 | | 200 | 3463889 | 201.04 | 100.52 | 100.52 ± 0.009 | 200 | 3464117 | 201.05 | 100.53 | | 220 | 3811741 | 221.23 | 100.56 | | 220 | 3812077 | 221.25 | 100.57 | 100.56 ± 0.007 | 220 | 3811562 | 221.22 | 100.56 | | 240 | 4168397 | 241.93 | 100.80 | | 240 | 4167556 | 241.88 | 100.78 | 100.79 ± 0.012 | 240 | 4167502 | 241.88 | 100.78 | |
| Drug-matrix solution | 160 | 2773303 | 160.96 | 100.60 | | 160 | 2772297 | 160.90 | 100.56 | 100.57 ± 0.024 | 160 | 2772063 | 160.89 | 100.56 | | 180 | 3119142 | 181.03 | 100.60 | | 180 | 3121001 | 181.14 | 100.66 | 100.63 ± 0.030 | 180 | 3119725 | 181.06 | 100.62 | | 200 | 3477174 | 201.81 | 100.90 | | 200 | 3477005 | 201.80 | 100.90 | 100.91 ± 0.015 | 200 | 3477987 | 201.86 | 100.92 | | 220 | 3831775 | 222.39 | 101.10 | | 220 | 3831000 | 222.35 | 101.08 | 101.08 ± 0.025 | 220 | 3829872 | 222.28 | 101.05 | | 240 | 4185580 | 242.92 | 101.20 | | 240 | 4186378 | 242.97 | 101.22 | 101.21 ± 0.011 | 240 | 4185596 | 242.92 | 101.20 | |
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