Stability-Indicating Gradient RP-LC Method for the Determination of Process and Degradation Impurities in Bosentan Monohydrate: An Endothelin Receptor Antagonist
Figure 2
Typical RP-LC chromatograms of (a) bosentan monohydrate unspiked test preparation (b) bosentan monohydrate spiked test preparation with known impurities (Imp-A, Imp-B, Imp-C, Imp-D, and Imp-E).