Research Article
Stability-Indicating RP-TLC/Densitometry Determination of Raloxifene Hydrochloride in Bulk Material and in Tablets
Table 3
Robustness of the method.
| | Parameter | ±SD of peak area | % RSD |
| | Mobile-phase composition: methanol : water : ammonia (96 : 04 : 0.1 v/v) | 50.89 | 1.5 | | Mobile-phase composition: methanol : water : ammonia (94 : 06 : 0.1 v/v) | 52.74 | 1.6 | | Mobile-phase volume (±2 mL) | 47.91 | 1.4 | | Development distance (±0.5 cm) | 44.03 | 1.3 | | Activation of TLC plate (±5 min) | 48.84 | 0.9 | | Duration of saturation (±5min) | 44.97 | 1.4 | | Time from spotting to chromatography (±10 min) | 40.16 | 0.9 | | Time from chromatography to scanning (±10 min) | 49.34 | 1.2 |
|
|
