Research Article

Pharmacokinetics of Single-Dose and Multi-Dose of Lovastatin/Niacin ER Tablet in Healthy Volunteers

Table 2

Intra- and interrun precision and accuracy of determination of NA, NAM, NUA, and lovastatin in human plasma.

ConcentrationRSD (%)
NominalFound Intrarun ( )Interrun ( )

NA (μg/mL)0.009840.01016.012.7
0.2460.2374.28.3
8.868.713.78.5

NAM (μg/mL)0.01020.01035.512.0
0.2540.2713.59.3
9.149.583.213.5

NUA (μg/mL)0.009930.01034.82.0
0.2480.2682.311.3
8.949.522.313.0

Lovastatin (ng/mL)0.10340.10518.214.9
2.5852.6885.08.6
36.1937.096.69.7