Chromatography Research International / 2013 / Article / Tab 9 / Research Article
Development and Validation of a Stability-Indicating RP-HPLC Method for the Simultaneous Estimation of Guaifenesin and Dextromethorphan Impurities in Pharmaceutical Formulations Table 9 Regression statistics.
Substance Linearity range (
g mL−1 ) Correlation coefficient (
)
-intercept bias in %GN-Impurity A 0.93 to 239.61 0.999 0.9 GN-Impurity B 2.01 to 242.78 0.999 1.0 GN-Impurity C 1.26 to 241.92 1.000 0.7 GN-Impurity D 0.79 to 242.55 0.999 0.8 DN-Impurity A 0.17 to 14.10 1.000 0.4 DN-Impurity B 0.25 to 10.10 1.000 0.1 DN-Impurity C 0.27 to 12.23 1.000 0.8 DN-N-oxide 0.19 to 12.49 1.000 0.6 DN-NFM Impurity 0.19 to 12.19 0.998 1.5 DN-NFO Impurity 0.48 to 12.22 1.000 0.9 GN 1.53 to 244.78 0.999 1.6 DN 0.18 to 12.15 1.000 0.1